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Additional information
Additional Information
Market: LSE
Sector: Pharmaceuticals
Epic: ATD
News: Latest news
Web Site: Asterand
Other Articles: 08-07-201014-06-201014-06-2010

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Asterand

Asterand

Asterand plc is the leading global supplier of high quality, well characterized human tissue and human tissue-based research services to drug discovery scientists. Their mission is to provide human tissues and services to accelerate the identification and validation of drug targets and enhance the selection of drug candidates with an increased likelihood of clinical success.

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Thursday, February 04, 2010

Asterand posts documentation on proposed BioSeek acquisition to shareholders

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Asterand PLC (LSE: ATD) said the circular and the notice of a general meeting relating to the proposed acquisition of BioSeek Inc has been sent to shareholders this week.

The meeting is to be held on February 18 at Asterand’s Royston office in Hertfordshire.

Asterand announced its plan to buy privately-held drug discovery services company BioSeek for up to US$14 million in cash and shares, dependent on sales performance in 2010, when it issued an interim Management statement on November 18.

The proposed acquisition of BioSeek will be Asterand's first step in its "buy and build" strategy to consolidate leadership in the global human tissue and human tissue based services market. It believes BioSeek is highly complementary to Asterand's business in terms of both products and services offered.

Asterand signed an agreement to buy BioSeek for an initial US$1.0 million in shares and a further up to US$13 million in 2011 depending on the level of sales growth achieved by BioSeek in the twelve months ended 31 December 2010.  The the first US$3.0 million of such payment will be made in Asterand shares, and any additional payment will be in cash or shares, at Asterand's discretion.

BioSeek has developed proprietary human primary cell based, high throughput assay systems (BioMAP) designed to replicate the intricate cell and pathway interactions present in inflammatory, autoimmune and cardiovascular diseases. The system predicts clinical activities of a potential drug candidate through comparison of assay results to a proprietary database of data profiles for known compounds. The BioMAP platform provides pharmaceutical companies with actionable data to guide their lead selection and optimization programmes.

BioSeek is located in South San Francisco and has 14 employees.

In addition to service revenue, BioSeek's growth has been financed by venture investors Bay City Capital and Fremont Ventures and a research collaboration and strategic investment by Amylin Pharmaceuticals Inc (Nasdaq: AMLN).  In addition to Amylin, BioSeek has had collaborations with numerous pharmaceutical and biotechnology companies including Merck-Serono, UCB, and Dainippon Sumitomo.

Asterand intends to maintain the South San Francisco site and staff, and BioSeek's key managers will be joining Asterand's senior management team.

In the year to end-December 2008, BioSeek reported revenues of US$3.2 million and a pretax loss of US$4.1 million. The audited value of the gross assets being acquired is US$10.1 million.

BioSeek's sales to date have been achieved with limited resource - Asterand brings scale to the selling process. Asterand has strong connections with many pharmaceutical companies where BioSeek has historically had little or no exposure or penetration. This expanded global sales coverage should increase awareness and adoption of BioMAP. The platform is automated and easily expanded, and investment has been made in equipment and facilities so that additional demand can be met with relatively smaller additional costs.

Asterand anticipates that the proposed acquisition will be marginally loss-making or break-even in the first year of ownership and will increasingly contribute to earnings thereafter.

Asterand also announced, earlier this week, it is seeking to fill a chief scientific officer position, to be based in either San Francisco or Detroit. This new role will be responsible for establishing and leading the scientific strategic positioning and direction of Asterand.

The group is looking for an individual it described as a “door opener” at a senior scientific level in pharma companies, who has similar connections with government and regulatory bodies as well as an established set of contacts with key opinion leaders.

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