Antisoma plc - Director Shareholding

Director Shareholding Antisoma plc Company Executive Incentive Plan grant London, UK, and Cambridge, MA: 23 February 2009 Pursuant to the Antisoma plc Executive Incentive Plan, Antisoma plc has granted Performance Share awards over ordinary 1p shares to Directors as follows: Director Number of Performance Shares Glyn Edwards 693,182 Ursula Ney 509,091 Eric Dodd 363,636 Other employees have also been granted Performance Share awards over a total of 2,225,000 shares. The above Performance Share grant reflects the Company's practice of making biannual awards to qualifying employees following release of the interim and preliminary financial results. The above Directors and certain employees have agreed to pay the employer's National Insurance arising on the exercise of their own options. The Performance Share awards, which are subject to fulfilment of certain performance and other conditions, have a date of grant of 19 February 2009 and will normally become exercisable for three years, commencing on 19 February 2012. The Performance Shares are exercisable at 1p each. Mr Edwards, Dr Ney and Mr Dodd, as Directors, notified Antisoma plc of their respective interests in these shares on 19 February 2009. Enquiries: Alison Saville, Communications Executive +44 (0)20 3249 2100 Antisoma plc ---END OF MESSAGE--- This announcement was originally distributed by Hugin. The issuer is solely responsible for the content of this announcement.

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