Proactive Investors - Run By Investors For Investors

Imugene Ltd gets site approval for gastric cancer study in Thailand

Imugene Ltd gets site approval for gastric cancer study in Thailand

Imugene Ltd (ASX:IMU) has received approval from the Faculty of Medicine, Chiang Mai University of Thailand to start site activation process for the Phase 1b/2 study of its HER-Vaxx immuno-oncology therapy in gastric cancer.

HER-Vaxx is a cancer immunotherapy designed to treat HER-2 positive gastric cancer, a cancer with increased levels of a growth-promoting protein called the HER-2 receptor.

Immuno-oncology is a relatively new but highly promising field that uses the method of activating a patient's immune system against tumour growth.

The approval in Thailand follows approvals from Taipei Veterans General Hospital in Taiwan and the University of Hong Kong.

Thailand, Taiwan and Hong Kong and are three of the eight study sites participating in the initial Phase 1b portion of the upcoming Phase 1b/2 study.

The initial Phase 1b will enrol up to 18 patients to be treated with HER-Vaxx in combination with chemotherapy to interrogate three dose levels.

This first stage is to obtain safety, immunogenicity (a measure of how many of the HER-2 antibodies are produced), evaluate the booster schedule and determine the optimal dose to take into the Phase 2 study.

The larger, open label Phase 2 study will enrol around 68 patients randomised into two arms of either HER-Vaxx plus standard-of-care or standard-of-care alone.

Gastric cancer represents an area of high unmet medical need, particularly in Asian countries.

Imugene had $1.6 million in cash as at 30 June 2016.

 

Proactive Investors is a global leader reporting financial news, media, research and hosts events for listed emerging growth companies and investors across four continents.

View full IMU profile View Profile

Imugene Ltd Timeline

Related Articles

cannabis
February 27 2019
The company is a leader for dried flower vaporizers, and a pioneer in cannabis telemedicine and AI technologies
antibodies
May 02 2019
Avacta is using Affimers to develop its own cancer therapy, but it also licenses the technology to other companies, including major pharma group ModernaTX and LG Chem Life Sciences
1537236236_main-better-use.jpg
September 17 2018
The company is utilising technology and big data to tackle the growing healthcare crisis and personalise treatment options for preventative care.
Copyright © Proactiveinvestors.com, 2019. All Rights Reserved - Proactive Investors North America Inc., Proactive Investors LLC

Market Indices, Commodities and Regulatory News Headlines copyright © Morningstar. Data delayed 15 minutes unless otherwise indicated. Terms of use