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Bristol-Myers announces results for Opdivo

Bristol-Myers Squibb Company on Tuesday announced updated results for Opdivo monotherapy

Updated results for Opdivo monotherapy

Bristol-Myers Squibb Company (NYSE:BMY) on Tuesday announced updated results for Opdivo monotherapy.

The pharma said that Opdivo monotherapy (3 mg/kg every two weeks [n=98]) and in combination with Yervoy (Opdivo 1 mg/kg plus Yervoy 3 mg/kg every three weeks [n=61]) in previously treated small cell lung cancer (SCLC) patients, a cohort of the Phase 1/2 open-label CheckMate -032 trial.

The confirmed objective response rate (primary objective) was 25% (95% CI: 15, 37) in patients who received Opdivo plus Yervoy and was 11% (95% CI: 6, 19) with Opdivo alone with additional follow-up.

Response was observed regardless of platinum sensitivity or prior lines of therapy. With the combination, three patients experienced a complete response.

The estimated two-year overall survival rate (secondary objective) was 30% with Opdivo plus Yervoy and was 17% with Opdivo alone. In this updated analysis, no new safety signals were observed. Grade 3/4 treatment-related discontinuation rates were 10% in the Opdivo plus Yervoy group and 4% in the Opdivo group.

Bristol-Myers shares closed up 0.9% at $56.03 on Tuesday.

Quick facts: Bristol-Myers Squibb Co

Price: 64.16 USD

Market: NYSE
Market Cap: $150.4 billion

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