US stocks are seen starting in the red after a mixed finish, while European indices are also down in the dumps as Trump trade fears persist.
In London, FTSE 100 is just about hanging onto gains, around flat at 7,628 as investors await the latest interest rate decision from the central bank.
Both the German DAX and France's CAC 40 are lower too in morning deals.
On Wall Street on Wednesday, the Dow Jones Industrial Average closed down over 42 at 24,657. The Nasdaq added over 55 points at 7,781, while the S&P 500 added 4.73 at 2,767.
In futures today, the Dow Jones is 93 points lower, the S&P 500 is eight points down and the Nasdaq is 21.5 points off.
“European equity markets have been drifting lower this morning as trade fears persist,” said David Madden, analyst at London spreadbetter at CMC Markets.
“The standoff between the US and China has worried investors that the EU could be in line for similar treatment.”
In Asia overnight, the Nikkei 225 in Japan gained over 137 points at 22,693,, boosted by machine and tech stocks.
Elsewhere, the Shanghai Composite Index in China shed nearly 40 points at 2,875 as traders fled from risk.