Proactive Investors - Run By Investors For Investors

Achieve Life Sciences shares climb following positive results from its smoking cessation study

Its plant-based compound cystine is meant to reduce nicotine withdrawal symptoms
Man breaking a cigarette in half
The Washington-based biotech develops smoking cessation aids

Achieve Life Sciences Inc (NASDAQ:ACHV) shares soared double digits following the announcement of positive clinical study results of its smoking cessation treatment.

The clinical-stage pharmaceutical company conducted a study looking into the effect of food on cystine’s bioavailability, which refers to the rate at which a drug is absorbed into the system.

Shares of the Washington-based biotech jumped nearly 38% to $3.76 in Thursday pre-market trading.

READ: Achieve Life Sciences shares rise on release of new plan for smoking cessation drug

The plant-based compound interacts with the brain’s nicotine receptors to reduce nicotine withdrawal symptoms.

The study took a look at the bioavailability of a new formulation of 3 mg of cystine in 12 healthy volunteer smokers under fed and fasted conditions.

The results showed that cystine was absorbed with maximum concentration levels observed in the blood within less than two hours, with or without food.

"We believe this new cytisine formulation will allow for an extended shelf-life and will be used in the upcoming Phase 2b clinical trial as well as the Phase 3 clinical program," said CEO Rick Stewart in the company’s press release.

Similar results were found in the study evaluating the previous cystine formulation in 24 healthy non-smoking volunteers.

Tobacco use is the leading cause of preventable death, responsible for nearly six million deaths annually worldwide, according to the World Health Organization’s Report on the Global Tobacco Epidemic.

View full ACHV profile View Profile

Achieve Life Sciences Inc Timeline

Related Articles

January 04 2019
In its outlook for 2019, the firm said the focus was now “not only on continuous improvements in feed grade and recoveries but on expanding the business into new jurisdictions”
November 20 2018
Borko Moric will succeed Parilla as chief executive officer. Bojan Moric will become the company's chief operations officer
Copyright ©, 2019. All Rights Reserved - Proactive Investors North America Inc., Proactive Investors LLC

Market Indices, Commodities and Regulatory News Headlines copyright © Morningstar. Data delayed 15 minutes unless otherwise indicated. Terms of use