viewe-Therapeutics PLC

E-Therapeutics chief Young looks forward to major clinical milestones

E-Therapeutics chief Dr Malcolm Young today said he is looking forward to some major clinical milestones after a year of significant progress.



E-Therapeutics (LON:ETX) chief Dr Malcolm Young today said he is looking forward to some major clinical milestones after a year of significant progress.

The AIM quoted drug developer’s interim results this morning revealed that it had enough working capital to see it through to mid-2014.

Clinical trials got underway during the period for the company’s lead cancer drug, with a phase I trial in the US for patients with brain cancer and a phase I trial in UK patients with solid tumours. The first data is expected later this year, before final results in 2013 and 2014 respectively.

The company has also advanced a number of other development programmes including treatments for ‘major depressive disorder, MRSA and C.dificile.

The increased investment during this busy period and led to an increased loss of £1.8 mln (H1 2011: £1.5 mln), though E-Therapeutics says it still has a strong balance sheet with £11.7 mln of cash remaining.

The longer term funding strategy is to attract licensing partners for the late-stage drug development work and commercialisation. Two drug candidates are currently the priority – the cancer drugs and the antidepressant.

“We are now close to reporting our first clinical data since our refinancing in 2011,” the company said.

“Initial findings from the cancer programme with ETS2101 will be followed next year by more extensive data, with final results from the brain cancer study expected in late 2013 and final results from the solid tumour study expected in Q1 2014, followed soon afterwards by data from the phase IIb trial of our antidepressant, ETS6103.

“Advancing these two drugs rapidly towards potential partnering deals is our key priority, but we are also very enthusiastic about applying our unique discovery platform to generate further new candidates that will fuel long-term growth.”

City broker Panmure Gordon described today’s financials as ‘better than expected’ and said it remains a buyer of the shares.

“e -Therapeutics possesses a technology platform that could revolutionise the way the pharmaceutical industry conducts drug development,” analyst Savvas Neophytou said in a note to clients.

“The platform is increasingly accepted as credible, and the company has intellectual property that puts it in a position of strength, which may necessitate others paying it a licensing fee or, alternatively, result in the company being acquired.”


Quick facts: e-Therapeutics PLC

Price: 14.75 GBX

Market: AIM
Market Cap: £61.81 m

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